Endocrine Abstracts

Adrenal incidentalomas are incidentally discovered adrenal tumors by imaging methods without any prior suspicions of adrenal disease. Most of these tumors are functionally inactive but thorough investigations can reveal discrete hormone excess. Chromogranin A(CgA) is expressed in neuroendocrine cells throughout the body, including large and small intestine, adrenal medulla and pancreatic islets. It is a marker for carcinoid tumors, paragangliomas, and other neuroendocrine tumo...

Subclinical hypothyroidism is defined as a biochemical abnormality characterized by an elevated serum level of sTSH with normal thyroid hormones (FT4) and no clinical symptoms. The objective of this study was to asses whether patients with subclinical hypothyroidism have a risk of hypercholesterolemia. We have evaluated 37 adults (34 female and 3 male), mean age 49.20±9.65 years, with laboratory confirmed subclinical hypothyroidism, sTSH value above of 4.5 mU/L and normal...

Background: Women with polycystic ovary syndrome (PCOS) appear at increased cardiovascular risk due in part to a dyslipidemia characterized by increased plasma triglyceride and reduced high density lipoprotein (HDL) cholesterol levels. Obesity, insulin resistance and hyperandrogenemia are features of PCOS and potentially affect lipid metabolism. On the other hand, obesity has an important influence on the lipid metabolism.Objectives: The aim of this stud...

Premature ovarian failure (POF) is characterized by amenorrhea, hypergonadotropism and hypoestrogensm in women under 40 years. Sex steroids play an important role in maintaining bone mass and cessation of ovarian function results in significant bone loss.Objective: To evaluate bone mass density (BMD) and factors influencing it in women with POF.Design & methods: First group of 144 women with spontaneous POF (I), 39.7±7.6 y...

Adrenal incidentalomas are referred as clinically silent adrenal masses discovered incidentally during diagnostic testing or treatment for conditions not related to suspicion of adrenal disease. Certain percent of them are hormonally active and autonomous cortisol secretion is reported with increasing frequency. The aim of the study was to assess value of 1mg-DST in subclinical Cushing’s syndrome (CS) compared to the other forms of adrenal incidentalomas. We have evaluate...